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Will 850nm Or 940nm Penetrate Deeper In White Skin

New 2015 version of this article has been published.

-Vladimir

ane. Preface

put on the red light

"Penetrating red light is possibly the central anti-stress factor for all organisms.The chronic deficiency of such lite is, I call back, the best explanation for the deterioration which occurs with aging."?– Ray Peat

*

During the concluding summer, I spent quite a lot fourth dimension reading Ray Peat's articles. In many of his articles, Peat writes that darkness and bluish light can exist harmful for health, and red calorie-free is healthy.

Peat doesn't give many references to justify those claims, but nevertheless, at that place exists a tremendous amount of report data supporting his views.

Certain wavelengths of electromagnetic radiation directly increase ATP-levels in the tissues, mainly by activating the mitochondrial enzyme?cytochrome c oxidase?(Cox). The most relevant wavelengths are 600-1000nm–in other words, reddish light and the penetrating shorter wavelengths of near-infrared radiations (NIR).[1-4]

On the other mitt, blue light tin can?inhibit'the same enzyme (Cox), and this can atomic number 82 to?retinal damage?and other problems.[5,6]

ii. The health furnishings of red lite and near-infrared radiation: The extent of the research

Cherry-red light'southward positive effects on health are not a recent finding. The earliest reports on the topic?have been published in the 19th century, the most well-known commodity being?The Ruddy Light Treatment of Small-Pox?(1895)?by Niels Finsen, who also got the 1903 Nobel Prize in medicine for his inquiry regarding the health furnishings of light.[7]

In 1910, John Harvey Kellogg published his 200-page book?Light Therapeutics, which included?a large amount of information near the therapeutic usefulness of light therapy past incandescent light bulbs and
arc lights.[8, see too Appendix iii]

In this writing, I volition focus on the contemporary research, most of which has been?usually studied with depression-level laser therapy devices (coherent light). Only during this year (2013), dozens of controlled homo studies take been published on this subject. Many of the studies are also placebo-controlled, because low-ability virtually-infrared light is invisible and doesn't emit heat.

According to the studies, many different illnesses tin can be treated with this kind of light therapy. Many of the results have been very encouraging. Hither'due south a list of some illnesses/bug that could be, according to the studies, finer treated with red light and/or infrared:

  • Acne [9]
  • Achilles tendinitis [x]
  • Angina pectoris [11]
  • Aphthous stomatitis [12,13]
  • Body contouring [14,xv]
  • Chemotherapy-induced oral mucositis [16-xix]
  • Cholesterol levels [20,21]
  • Chronic autoimmune thyroiditis [22,23]
  • Chronic myofascial pain in the neck [24]
  • Chronic rhinosinusitis [25,26]
  • Depression/mood [27-29]
  • Dry rima oris / xerostomia [30,31]
  • Dysmenorrea [32]
  • Fibromyalgia [33,34]
  • Gingivitis [35-38]
  • Mitt-pes-and-oral fissure disease [39]
  • Herpes labialis [xl-45]
  • Genu osteoarthritis [46-49]
  • Lateral epicondylitis [50]
  • Lymphedema (breast cancer-related) [51,52]
  • Macular degeneration, age-related [53]
  • Male androgenetic alopecia [54,55]
  • Myopia (degenerative/progressive) [56]
  • Onychomycosis [57]
  • Orofacial myofunctional conditions [58]
  • Photoaged skin [59,60]
  • Pressure level ulcer [61]
  • Raynaud'south miracle [62]
  • Recovery from 3rd molar extraction [63]
  • Restless legs syndrome [64,65]
  • Pare ulcers [66]
  • Sleep quality [67]
  • UVB-induced erythema (prevention of sunburns) [68]
  • Wound healing [69]

(The treatment methods vary between the studies, and this might explain varying report results.)

Many animal studies have likewise been conducted (encounter Appendix two).

3. The health effects of red light and virtually-infrared radiation: A few examples of the clinical study results

Age-related macular degeneration

Researchers in the University of Heidenberg conducted a large trial of 200 subjects, in which they medicated elderly people with and without cataracts by near-infrared lite (using low level light amplification by stimulated emission of radiation).[53]

The intervention group was treated four times during ii weeks. Placebo group was given a mock treatment.

Placebo didn't affect bailiwick's vision, simply of the patients getting infrared, 95% saw meaning improvements in their vision. A big portion of the patients were able to come across a few rows lower on the?Snellen nautical chart.The improved vision was maintained for 3-36 months after treatment.

Knee Osteoarthritis

Hungarian researchers studied the utilise of almost-infrared low-cal in articulatio genus osteoarthritis patients, in a double-blinded placebo controlled trial

Intervention group got infrared handling on their afflicted joint twice a week, over a period of four weeks.The placebo grouping got a similar handling of 100-fold lower intensity.[46]

In the intervention group, the pain scores were (on a scale from 1 to 10):
– 5.75 earlier the treatment
– 1.71 after the last handling session
– 1.18 two months after completing the therapy

In the placebo group, the pain scores were:
– 5.62 before handling
– 4.13 later the last treatment session
– 4.12 two months after completing the therapy

Labial herpes

The researchers of Academy of Vienna Medical School studied the usage of red light on labial canker in a double-bullheaded, placebo-controlled trial.[forty]

The subjects were treated in a recurrence-free menstruum.The intervention group were treated for 10 minutes daily for two weeks with visible red light (depression-level laser). Placebo group got a similar treatment, but the laser wasn't turned on. The subjects wore masks, so that they couldn't see whether they were given the real treatment.

The patients were instructed to return to the department at the time of symptom recurrence. In the placebo grouping, the symptoms recurred.The median recurrence-gratuitous interval in the laser-treated grouping was 37.v wk compared with three wk in the placebo group.

4. The systemic anti-inflammatory effect

Usually the red/almost-infrared is applied locally to the treatable tissue. However, light likewise has systemic furnishings which seem to be transmitted mainly by circulation of blood. The researcher?Natalya Zhevago?has conducted an interesting'study, in which the patients got some?visible light and infrared'to the sacral area (low back).[70] The given light was quite similar to sunlight, except that this light didn't comprise UV radiations or bluish light, and the infrared portion was polarized. Co-ordinate to one'written report, polarization of calorie-free enhances the metabolic effect slightly.[71]

The subjects' blood was analyzed later on the treatment. The results were interesting. Subjects' pro-inflammatory cytokines (TNF-?, IL-half-dozen etc.) were?dramatically?reduced in the subjects, specially in those with initially high values. Also, the concentration of?anti-inflammatory cytokines increased.[70]

A dramatic decrease in the level of pro-inflammatory cytokines?TNF-?, IL-6, and IFN-??was revealed: at 0.5 h later on exposure of volunteers (with the initial parameters exceeding the norm),'the cytokine contents fell, on boilerplate, 34, 12, and ane.five times[…]

The effects were quite opposite to the typical furnishings of UV radiation, which?increases?TNF-? ja IL-6 and other pro-inflammatory cytokines.[72]

In human studies, large doses of?IL-6?and?TNF-??have been demonstrated to suppress peripheral thyroid hormone metabolism past decreasing T3 and increasing rT3.[73,74] We could likewise speculate, whether lack of sufficient therapeutic light could be one cause of the "rT3 dominance" and hypothyroid symptoms. In?i report, half of the hypothyroid patients getting near-infrared treatment did not crave any medication through the 9-calendar month follow-upward after the handling period, establishing the importance of calorie-free for thyroid health.[22]

5. Low-cal sources (laser, LED, lite bulbs, oestrus lamps, sunlight)

"Many people who came to cloudy Eugene to study, and who often lived in cheap basement apartments, would develop chronic wellness bug within a few months. Women who had been healthy when they arrived would oft develop premenstrual syndrome or arthritis or colitis during their first winter in Eugene."?- Ray Peat

red light therapyIn the studies conducted in contempo years, red light and about-infrared accept been studied mostly with coherent (laser) lite devices. Some animal studies have besides been conducted with lite-emitting diodes (LEDs), eg. many?of?Janis Eells' studies.

Despite the fact that most of the studies used?coherent?light (laser), the coherence?of the light?is not a requirement for the therapeutic effects, and then other low-cal sources can be used therapeutically too. This?was?stated?long agone?past a leading researcher,?Tiina Karu, and has been confirmed in a?review?article by?Harvard researchers.[75] And as mentioned above, J. H. Kellogg has reported the immensely constructive therapeutic apply of incandescent bulbs equally early as in 1910 (see Appendix 3).

When I was writing my?Circadian Rhythms?essay, I used to think about the possible explanations of the therapeutic effects of walking outdoors. Sunlight tin can increment the production of vitamin D and it can besides suppress melatonin, but now nosotros have a brand new mechanism to explain?why it'south adept to spend time outdoors.

A review commodity?on this subject states that in fundamental Europe, the corporeality of IR-A radiation is express to 20mW/cm2, which is actually quite a proficient amount compared to the power of the devices used in the low-level laser studies.[1] On the other hand, the wavelengths aren't optimized (to the assimilation peaks) equally in the laser studies, and daylight as well contains UV radiation and blue light, which might reduce the benefits of ruby-red lite. It should as well be remembered that virtually-infrared radiations doesn't penetrate through the clothes.

In the indoors,?element of group vii lamps,?incandescent lamps?and rut lamps are practiced sources of cerise and virtually-infrared calorie-free, at least if they're held?close enough'to the peel. Heat lamps by?Philips?or?Osram?accept quite a good spectrum with low corporeality of blueish low-cal, but a large amount of their power is emitted every bit warming IR-B radiation, and only ~12% of the power is emitted as the therapeutic wavelengths (600-1000nm). However, the heat lamps are often high ability (upwards to 250W), then they still emit quite a significant amount of therapeutic wavelengths.

Because of the?phase-out of incandescent lamps, it will presently be increasingly difficult to get typical incandescent lamps of sufficient power, so in the?future oestrus lamps might be the most applied choice. It's somewhat sad that the incandescent lamps are going to exist replaced with meaty fluorescent lamps (CFL), because they don't usually emit significant amount of protective carmine and about-infrared light. This is the reason why some of the researchers, such as?Richard Funk?and?Alexander Wunsch,?who likewise appeared in the?Bulb Fiction documentary, take stated that increment in the CFL usage might exist harmful to citizens' eyes.

The possible benefits of infrared saunas aren't ordinarily based on this aforementioned mechanism, because most of the saunas don't emit the therapeutic wavelengths of 600-1000nm. For instance, in one infrared sauna?report, the sauna emitted infrared in the wavelength range of 5000-1000000 nanometres.

Theoretically, LEDs and lasers with optimized wavelengths would be the best choice, but to this appointment, the products aren't very inexpensive for the consumers. In theory, the optimal device emits just wavelengths of 700-950nm, and so the light would exist invisible and wouldn't emit any heat, but still information technology would produce the therapeutic health benefits by increasing the part of Cox.

half dozen. Conclusion

The important biological effects of ruby-red light were known even dorsum in the 19th century, notwithstanding very few of the biologists seem to know about those findings present. The knowledge of the physiological furnishings of light is mainly limited to blue low-cal's furnishings on circadian rhythm, yet the importance of scarlet and nearly-infrared light is probably a more than important topic for the public health.

The general therapeutic usefulness of red lite reminds me of the therapeutic uses of thyroid hormone, the topic about which I've?written before. This connectedness is actually quite logical, considering that thyroid hormone also?increases Cox activity, by?increasing the cardiolipin?concentration in the mitochondria.[76,77]

Fourth dimension volition tell whether various treatments based on blood-red and virtually-infrared light will gain popularity in the near time to come. But they should, considering the study results are thoroughly so positive.

About the writer

Vladimir Heiskanen2 Vladimir Heiskanen of Finland has been researching and writing virtually health for several years. Currently a chemistry student at the Academy of Helsinki and a blogger since 2010, he has a keen interest in human being biology, and has studied scores of books, reports and cutting-edge health websites, especially the work of Chris Masterjohn, Paul Jaminet, and?Matt Rock. You can read all of?his fascinating?articles published at 180D HERE.

References

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[2] Karu et al: Irradiation with He-Ne laser increases ATP level in cells cultivated in vitro. (1995)

[3] Benedicenti et al: Intracellular ATP level increases in lymphocytes irradiated with infrared laser light of wavelength 904 nm. (2008)

[four] Lapchatk et al: Transcranial near infrared laser treatment (NILT) increases cortical adenosine-five?-triphosphate (ATP) content following embolic strokes in rabbits. (2010)

[5] Osborne et al: A hypothesis to suggest that light is a risk factor in glaucoma and the mitochondrial optic neuropathies (2008)

[six] Nick Lane: Are mitochondria the alpha and omega of retinal disease? (2006)

[7] Niels R. Finsen: The Red Light Treatment of Pocket-size-Pox (1895)

[8] John H. Kellogg: Low-cal therapeutics; a practical transmission of phototherapy for the student and the practitioner, with special reference to the incandescent electric-light bath (1910)

[nine] Aziz-Jalali et al: Comparing of Scarlet and Infrared Depression-level Laser Therapy in the Treatment of Acne Vulgaris. (2012)

[10] Bjordal et al: A randomised, placebo controlled trial of low level laser therapy for activated Achilles tendinitis with microdialysis measurement of peritendinous prostaglandin E2 concentrations. (2006)

[11] Babushkina et al: Results Of 10-Yr Apply Of Low Intensity Laser Therapy And Conventional Treatment Of Patients With Stenocardia

[12] Anand et al: Low level laser therapy in the treatment of aphthous ulcer. (2013)

[13] De Souza et al: Clinical evaluation of low-level light amplification by stimulated emission of radiation treatment for recurring aphthous stomatitis. (2010)

[14] Jackson et al: Depression-level laser therapy as a non-invasive approach for body contouring: a randomized, controlled study. (2009)

[fifteen] McRae&Boris: Independent evaluation of low-level laser therapy at 635 nm for non-invasive body contouring of the waist, hips, and thighs. (2013)

[16] Kuhn et al: Low-level infrared laser therapy in chemotherapy-induced oral mucositis: a randomized placebo-controlled trial in children. (2009)

[17] Gautam et al: Low level light amplification by stimulated emission of radiation therapy for concurrent chemoradiotherapy induced oral mucositis in caput and neck cancer patients – a triple blinded randomized controlled trial. (2012)

[eighteen] Antunes et al: Phase 3 trial of low-level laser therapy to prevent oral mucositis in caput and neck cancer patients treated with concurrent chemoradiation. (2013)

[19] Hodgson et al: Amelioration of oral mucositis hurting by NASA near-infrared lite-emitting diodes in bone marrow transplant patients. (2012)

[20] Jackson et al: Reduction in Cholesterol and Triglyceride Serum Levels Following Depression-Level Laser Irradiation: A Noncontrolled, Nonrandomized Pilot Study (2010)

[21] Maloney et al: The reduction in cholesterol and triglyceride serum levels following depression-level laser irradiation: a non-controlled, non-randomized airplane pilot study (2009)

[22] H?fling et al: Depression-level laser therapy in chronic autoimmune thyroiditis: a airplane pilot study. (2010)

[23] H?fling et al: Low-level laser in the treatment of patients with hypothyroidism induced by chronic autoimmune thyroiditis: a randomized, placebo-controlled clinical trial. (2013)

[24] Gur et al: Efficacy of 904 nm gallium arsenide low level laser therapy in the management of chronic myofascial pain in the neck: a double-blind and randomize-controlled trial. (2004)

[25] Naghdi et al: A airplane pilot study into the effect of low-level laser therapy in patients with chronic rhinosinusitis. (2013)

[26] Krespi&Kizhner: Phototherapy for chronic rhinosinusitis. (2011)

[27] Barrett&Gonzalez-Lima: Transcranial infrared laser stimulation produces beneficial cognitive and emotional furnishings in humans. (2013)

[28] Schiffer et al: Psychological benefits two and iv weeks afterwards a single treatment with near infrared light to the forehead: a airplane pilot study of 10 patients with major depression and anxiety. (2009)

[29] Meesters et al: Prophylactic treatment of seasonal affective disorder (SAD) by using lite visors: bright white or infrared lite? (1999)

[xxx] Vidovi? Juras et al: Effects of low-level light amplification by stimulated emission of radiation treatment on mouth dryness. (2010)

[31] Lon?ar et al: The result of depression-level laser therapy on salivary glands in patients with xerostomia. (2011)

[32] Shin et al: Skin adhesive low-level light therapy for dysmenorrhoea: a randomized, double-blind, placebo-controlled, pilot trial. (2012)

[33] G?r et al: Effects of low ability laser and low dose amitriptyline therapy on clinical symptoms and quality of life in fibromyalgia: a single-blind, placebo-controlled trial. (2002)

[34] Thousand?r et al: Efficacy of low power laser therapy in fibromyalgia: a single-bullheaded, placebo-controlled trial. (2002)

[35] Obradovi? et al: Depression-level lasers as an adjunct in periodontal therapy in patients with diabetes mellitus. (2012)

[36] Igic et al: Chronic gingivitis: the prevalence of periodontopathogens and therapy efficiency. (2012)

[37] Obradovi? et al: A histological evaluation of a low-level laser therapy as an adjunct to periodontal therapy in patients with diabetes mellitus. (2013)

[38] Makhlouf et al: Upshot of adjunctive low level laser therapy (LLLT) on nonsurgical treatment of chronic periodontitis. (2012)

[39] Toida et al: Usefulness of low-level light amplification by stimulated emission of radiation for control of painful stomatitis in patients with hand-pes-and-mouth affliction. (2003)

[forty] Schindl&Neumann: Low-intensity laser therapy is an constructive treatment for recurrent herpes simplex infection. Results from a randomized double-bullheaded placebo-controlled study. (1999)

[41] Mu?oz Sanchez et al: The event of 670-nm low laser therapy on herpes simplex type 1. (2012)

[42] Dougal&Lee: Evaluation of the efficacy of low-level lite therapy using 1072 nm infrared light for the treatment of herpes simplex labialis. (2013)

[43] Ferreira et al: Recurrent canker simplex infections: laser therapy as a potential tool for long-term successful treatment. (2011)

[44] de Carvalho et al: Effect of laser phototherapy on recurring herpes labialis prevention: an in vivo study. (2010)

[45] Eduardo Cde et al: Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy: a clinical protocol with 3-twelvemonth follow-up. (2012)

[46] Hegedus et al: The result of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial. (2009)

[47] Gur et al: Efficacy of different therapy regimes of low-power laser in painful osteoarthritis of the human knee: a double-blind and randomized-controlled trial. (2003)

[48] Stelian et al: Improvement of pain and disability in elderly patients with degenerative osteoarthritis of the genu treated with narrow-ring light therapy. (1992)

[49] Alghadir et al: Outcome of low-level light amplification by stimulated emission of radiation therapy in patients with chronic knee joint osteoarthritis: a single-blinded randomized clinical study. (2013)

[l] Lam&Cheing: Effects of 904-nm depression-level laser therapy in the direction of lateral epicondylitis: a randomized controlled trial. (2007)

[51] Ridner et al: A pilot randomized trial evaluating low-level laser therapy every bit an alternative treatment to manual lymphatic drainage for breast cancer-related lymphedema. (2013)

[52] Ahmed Omar et al: Treatment of post-mastectomy lymphedema with laser therapy: double bullheaded placebo control randomized study. (2011)

[53] Ivandic&Ivandic: Low-level laser therapy improves vision in patients with age-related macular degeneration. (2008)

[54] Leavitt et al: HairMax LaserComb laser phototherapy device in the treatment of male androgenetic alopecia: A randomized, double-blind, sham device-controlled, multicentre trial. (2009)

[55] Lanzafame et al: The growth of man scalp hair mediated past visible cherry calorie-free laser and LED sources in males. (2013)

[56] Shyrygina&Khadzhieva: [Effect of infrared depression-intensity laser therapy on orbital claret circulation in children with progressive short sightedness]. (2009)

[57] Landsman et al: Treatment of mild, moderate, and severe onychomycosis using 870- and 930-nm calorie-free exposure. (2010)

[58] Melchior Mde et al: Does low intensity laser therapy reduce pain and change orofacial myofunctional conditions? (2013)

[59] Baez&Reilly: The use of light-emitting diode therapy in the treatment of photoaged skin. (2007)

[60] Russell et al: A study to make up one's mind the efficacy of combination LED light therapy (633 nm and 830 nm) in facial peel rejuvenation. (2005)

[61] Schubert V: Furnishings of phototherapy on force per unit area ulcer healing in elderly patients subsequently a falling trauma. A prospective, randomized, controlled written report. (2001)

[62] Hirschl et al: Low level laser therapy in primary Raynaud's phenomenon–results of a placebo controlled, double blind intervention written report. (2004)

[63] Aras&G?ng?rm??: The effect of low-level laser therapy on trismus and facial swelling post-obit surgical extraction of a lower third tooth. (2009)

[64] Mitchell et al: Restless legs syndrome and about-infrared light: An culling treatment option. (2011)

[65] Mitchell et al: Comparing of 2 infrared devices in their effectiveness in reducing symptoms associated with RLS. (2011)

[66] Kubota J: Defocused diode laser therapy (830 nm) in the treatment of unresponsive skin ulcers: a preliminary trial. (2004)

[67] Zhao et al: Red Light and the Sleep Quality and Endurance Operation of Chinese Female Basketball game Players (2012)

[68] Barolet&Boucher: LED photoprevention: reduced MED response following multiple LED exposures. (2008)

[69] Simunovic et al: Wound healing of animal and human body sport and traffic accident injuries using low-level laser therapy handling: a randomized clinical report of seventy-four patients with control group. (2000)

[70] Zhevago&Samoilova: Pro- and Anti-inflammatory Cytokine Content in Human Peripheral Blood after Its Transcutaneous (in Vivo) and Direct (in Vitro) Irradiation with Polychromatic Visible and Infrared Light (2006)

[71] Barulin&Plavskii: Effect of Polarization and Coherence of Optical Radiations on Sturgeon Sperm Motility (2012)

[72] Bashir et al: UVB and proinflammatory cytokines synergistically activate TNF-alpha production in keratinocytes through enhanced gene transcription. (2009)

[73] Stouthard et al: Effects of acute and chronic interleukin-6 administration on thyroid hormone metabolism in humans. (1994)

[74] van der Poll et al: Tumor necrosis factor: a putative mediator of the ill euthyroid syndrome in man. (1990)

[75] Chung et al: The Nuts and Bolts of Low-level Light amplification by stimulated emission of radiation (Calorie-free) Therapy (2012)

[76] Paradies et al: Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats (1997)

[77] Jakovcic et al: Biochemical and stereological analysis of rat liver mitochondria in different thyroid states (1978)

Appendix one: Recommended manufactures


Chung et al: The Basics and Bolts of Depression-level Laser (Calorie-free) Therapy (2012)?"It was originally believed that the coherence of laser light was crucial to attain the therapeutic effects of LLLT, simply recently this notion has been challenged by the use of LEDs, which emit non-coherent light over a wider range of wavelengths than lasers. It has yet to be adamant whether in that location is a real difference between laser and LED, and if information technology indeed exists, whether the difference results from the coherence or the monochromaticity of laser lite, every bit opposed to the non-coherence and wider bandwidth of LED light."

Havelock Ellis: Sexual Education and Nakedness (1909)?"The hygienic value of nakedness is indicated by the robust health of the savage throughout the world who get naked. The vigor of the Irish, also, has been connected with the fact that (as Fynes Moryson's Itinerary shows) both sexes, fifty-fifty among persons of high social class, were accustomed to go naked except for a mantle, particularly in more remote parts of the state, until the sevcenteeth century. Wherever archaic races abandon nakedness for clothing, at in one case the trend to disease, bloodshed, and degeneracy notably increases, though it must exist remembered that the use of vesture is usually accompanied by the introduction of other bad habits.

Appendix 2: Animal studies (with positive results)

Rats:?laryngitis,?reflux laryngitis,?palatal mucoperiosteal wound healing,?bone metabolism,?peripheral nerve regeneration,astute articulation inflammation,?zymosan-induced arthritis,?tendon healing,?acute skeletal muscle injury,?MetSyn-related kidney injury,?streptozotocin-induced diabetic kidney,?heart failure-related inflammation,?cortical metabolic capacity and memory retention,?traumatic brain injury,?rheumatoid arthritis,?acute myocardial infarction,?second-degree burn down healing,?third-degree burn healing1?2?3,?lesions of diabetic retinopathy,?methanol-induced retinal toxicity ?

?

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